Détail de la notice
Titre du Document
Physical activity and risk of cognitive impairment and dementia in elderly persons
Auteur(s)
LAURIN Danielle ; VERREAULT René ; LINDSAY Joan ; ...
Résumé
Context: Dementia is common, costly, and highly age related. Little attention has been paid to the identification of modifiable lifestyle habits for its prevention. Objective: To explore the association between physical activity and the risk of cognitive impairment and dementia. Design, Setting, and Subjects: Data come from a community sample of 9008 randomly selected men and women 65 years or older, who were evaluated in the 1991-1992 Canadian Study of Health and Aging, a prospective cohort study of dementia. Of the 6434 eligible subjects who were cognitively normal at baseline, 4615 completed a 5-year follow-up. Screening and clinical evaluations were done at both waves of the study. In 1996-1997, 3894 remained without cognitive impairment, 436 were diagnosed as having cognitive impairment-no dementia, and 285 were diagnosed as having dementia. Main Outcome Measure: Incident cognitive impairment and dementia by levels of physical activity at baseline. Results: Compared with no exercise, physical activity was associated with lower risks of cognitive impairment, Alzheimer disease, and dementia of any type. Significant trends for increased protection with greater physical activity were observed. High levels of physical activity were associated with reduced risks of cognitive impairment (age-, sex-, and education-adjusted odds ratio, 0.58; 95% confidence interval, 0.41-0.83), Alzheimer disease (odds ratio, 0.50; 95% confidence interval, 0.28-0.90), and dementia of any type (odd
Editeur
American Medical Association
Identifiant
PMID : 11255456 ISSN : 0003-9942 CODEN : ARNEAS
Source
Archives of neurology (Chicago) A. 2001, vol. 58, n° 3, pp. 498-504 [bibl. : 61 ref.]
Langue
Anglais
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