Détail de la notice
Titre du Document
Environmental effects of human pharmaceuticals
Auteur(s)
SUMPTER John Phillip
Résumé
In the last few years, it has been demonstrated that many human pharmaceuticals are present in the aquatic environment, albeit at very low concentrations. Nevertheless, in at least one case, that of ethinyl estradiol, it is very likely that in some locations ethinyl estradiol is adversely affecting fish through its "feminization" of males. Another pharmaceutical, diclofenac, has caused the deaths of millions of vultures in Southeast Asia through its use in veterinary medicine. Those examples have highlighted our lack of understanding of fate, behavior, and effects of pharmaceuticals once they reach the environment. It is unclear presently whether these are isolated examples or whether there is a more general problem. If wildlife are to be protected from the effects of current and new pharmaceuticals, then our knowledge and understanding of this issue need to improve substantially. The recent European Medicines Agency guidelines covering the environmental risk assessment of human pharmaceuticals are a step in the right direction, but a more sophisticated approach, rather than a "one-fits-all" solution, is probably needed. Recent collaboration between industry scientists and academic ecotoxicologists is undoubtedly an encouraging development that is likely to markedly increase the quality, and hence value, of research undertaken in this area.
Editeur
Pergamon Press; Pergamon Press; Pergamon Press
Identifiant
ISSN : 0092-8615
Source
Drug information journal A. 2007, vol. 41, n° 2, pp. 143-147 [5 pages]
Langue
Anglais
Pour les membres de la communauté du CNRS, ce document est autorisé à la reproduction à titre gratuit.
Pour les membres des communautés hors CNRS, la reproduction de ce document à titre onéreux sera fournie sous réserve d’autorisation du Centre Français d’exploitation du droit de Copie.

Pour bénéficier de nos services (strictement destinés aux membres de la communauté CNRS (Centre National de la Recherche Scientifique), de l'ESR français (Enseignement Supérieur et Recherche), et du secteur public français & étranger) :