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Titre du Document
Open-label evaluation of azelastine nasal spray in patients with seasonal allergic rhinitis and nonallergic vasomotor rhinitis
Auteur(s)
LIEBERMAN Phil ; KALINER Michael A. ; WHEELER William J.
Résumé
Objective: The objective of the study was to evaluate the effectiveness of azelastine (Astelint) nasal spray, a topical second-generation antihistamine, in the treatment of symptoms of seasonal allergic rhinitis, seasonalallergic rhinitis with nonallergic triggers (mixed rhinitis), and nonallergic vasomotor rhinitis. Research design and methods. A total of 2343 primary care physicians, allergists, ENT specialists, and other health professionals participated in this 2-week, open-label evaluation of azelastine nasal spray. Data were collected through a physician questionnaire that included patient demographics, rhinitis diagnosis, medication history, and inclusion/ exclusion criteria; and two patient questionnaires that included symptom history, response to previous rhinitis medications, symptom control, and level of satisfaction with azelastine nasal spray. A completed physician questionnaire and two completed patient questionnaires were required for each patient to be included in the analysis. Patients who qualified for enrollment were given open-label azelastine nasal spray and instructed to administer 2 sprays per nostril twice daily for 2 weeks. Results: A total of 1225 heath professionals enrolled 7864 patients into the study. Completed physician and patient questionnaires were returned by 1081 health professionals and 5073 patients, 4364 of whom used azelastine nasal spray as their only rhinitis medication during the 2-week study period. The patients were predominantly c
Editeur
Librapharm
Identifiant
PMID : 15899111 ISSN : 0300-7995
Source
Current medical research and opinion A. 2005, vol. 21, n° 4, pp. 611-618 [8 pages]
Langue
Anglais
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