Détail de la notice
Titre du Document
Exposure to toxic elements via breast milk
Auteur(s)
OSKARSSON A. ; HALLEN I. P. ; SUNDBERG J.
Corporation(s) du ou des auteurs
Norwegian National Institute of Occupational Health Oslo NOR (Commanditaire); Institute Environmental and Health (McMaster University) USA (Commanditaire); University Toronto Toronto ON CAN (Commanditaire); International Union of Pure and Applied Chemistry (IUPAC) INT (Commanditaire); Commission on Toxicology. Clinical Chemistry Division INT (Commanditaire)
Résumé
Breast milk is the ideal nutrient for the newborn, but unfortunately also a route of excretion for some toxic substances. Very little attention has been paid to breast milk as a source of exposure to toxic elements. The dose-dependent excretion in breast milk and the uptake in the neonate of inorganic mercury, methylmercury and lead were studied in an experimental model for rats and mice.The transfer of mercuryfrom plasma to milk was found to be higher in dams exposed to inorganic mercury than to methylmercury. In contrast, the uptake of mercury from milk was higher in the sucklings of dams exposed to methylmercury than to inorganic mercury. Pre- and postnatal exposure to methylmercury resulted in increased numbers and altered proportions of the thymocyte subpopulation and increased lymphocyte activities in the offspring of mice and also effects on the levels of noradrenaline and nerve growth factor in the developing brain of rats. Mercury in blood and breast milk in lactating women in Sweden was studied in relation to the exposure to mercury from fish and amalgam. Law levels were found; the mean levels were 0.6 ng g-1 in milk and 2.3 ng g-1 in blood. There was a statistically significant correlation between mercury levels in blood and milk, showing that milk levels were approximately 30% of the levels in blood. Inorganic mercury exposure from amalgam was reflected in blood and milk mercury levels. Recent exposure to methylmercury from consumption of fish was refl
Editeur
Royal Society of Chemistry
Type du document
Conférence : Nordic symposium on trace elements in human health and disease, 5, Loen, NOR, 1994-06-19
Identifiant
PMID : 7741226 ISSN : 0003-2654 CODEN : ANALAO
Source
Analyst (London. 1877. Print) A. 1995, vol. 120, n° 3, pp. 765-770 [bibl. : 53 ref.]
Langue
Anglais
Pour les membres de la communauté du CNRS, ce document est autorisé à la reproduction à titre gratuit.
Pour les membres des communautés hors CNRS, la reproduction de ce document à titre onéreux sera fournie sous réserve d’autorisation du Centre Français d’exploitation du droit de Copie.

Pour bénéficier de nos services (strictement destinés aux membres de la communauté CNRS (Centre National de la Recherche Scientifique), de l'ESR français (Enseignement Supérieur et Recherche), et du secteur public français & étranger) :