Détail de la notice
Titre du Document
Effect of transjugular intrahepatic portosystemic shunt on quality of life
Auteur(s)
NAZARIAN G. K. ; FERRAL H. ; BJARNASON H. ; ...
Résumé
OBJECTIVE. The objective of this study was to determine the effect of the transjugular intrahepatic portosystemic shunt (TIPS) procedure on the quality of life. SUBJECTS AND METHODS. Data were collected on 99 patients who underwent the TIPS procedure between September 1991 and September 1995. Quality of life was assessed by the Karnofsky scale before and at intervals after the procedure. Procedure-related complications and other aspects of the patients' overall well-being, as reflected in liver and kidney function and nutritional status, were reviewed immediately before and after TIPS creation. Finally, mortality and TIPS patency rates were tabulated. RESULTS. We observed significantly improved quality of life. The quality of life remained significantly improved throughout the 24-month follow-up period. During the 1- to 3-month interval after the TIPS procedure, we observed in patients a significant decrease in blood urea nitrogen and an increase in albumin and bilirubin. During this period, patients had no significant change in liver enzymes, prothrombin time, ammonia, or creatinine. Complications of the TIPS procedure included a 30% incidence of new or worsened encephalopathy and a 15% incidence of other severe complications (intraperitoneal hemorrhage, severe accelerated liver failure). The procedure-related death rate was 5%. Longer term follow-up showed an overall sustained decrease in blood urea nitrogen, an increase in albumin, and a return of bilirubin to the pre-TIPS
Editeur
American Roentgen Ray Society
Identifiant
PMID : 8819395 ISSN : 0361-803X CODEN : AAJRDX
Source
American journal of roentgenology (1976) A. 1996, vol. 167, n° 4, pp. 963-969 [bibl. : 20 ref.]
Langue
Anglais
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