Détail de la notice
Titre du Document
Octreótido: Uma terapêutica Opcional para Quilotórax Pós-cirúrgico em Crianças com Cardiopatia Congénita
Octreotide: Additional conservative therapy for postoperative chylothorax in congenital heart disease
Auteur(s)
PARAMES Filipa ; FREITAS Isabel ; FRAGATA José ; ...
Résumé
Introduction: Chylothorax is a rare but serious postoperative condition in children with congenital heart disease. Conventional medical treatment consists of specific long-term dietary modification, and surgical reintervention, such as lymphatic duct ligation, may be indicated in refractory cases. In recent years, an additional conservative treatment, octreotide, a synthetic analog of somatostatin, has been used in management of congenital and postoperative chylothorax. Methods: The objective of this work was to analyze the efficacy and safety of this treatment for chylothorax after congenital heart surgery. We reviewed the records of sixteen patients with chylothorax after surgery for congenital heart disease between January 1999 and December 2007, and collected the following data: demographic information; type of surgical procedure; onset, duration and management of chylothorax and treatment; and duration of hospital stay. To analyze efficacy we compared these parameters in children receiving conventional treatment only with those receiving octreotide. To analyze safety we compared the adverse effects of both treatments. Octreotide was administered at a dose of 4 to 10 μg/kg/hour, with monitoring of side effects. Results: The incidence of chylothorax in our population was 1.6%. It occurred more often after Glenn and Fontan procedures (8 patients). Octreotide was begun three days after diagnosis of chylothorax and continued for a median of seventeen days (ranging from 4 to
Editeur
Sociedade Portuguesa de Cardiologia
Identifiant
ISSN : 0870-2551
Source
Revista portuguesa de cardiologia A. 2009, vol. 28, n° 7-8, pp. 799-807 [9 pages]
Langue
Portugais
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