Détail de la notice
Titre du Document
Adult-onset tic disorder, motor stereotypies, and behavioural disturbance associated with antibasal ganglia antibodies
Auteur(s)
EDWARDS Mark J. ; DALE Russell C. ; CHURCH Andrew J. ; ...
Résumé
The onset of tics in adulthood is rare and, unlike the childhood variety, there is commonly a secondary environmental cause. We present four cases (1 man, 3 women) with an adult onset tic disorder (mean age of onset, 36 years; range, 27-42 years) associated with the presence of serum antibasal ganglia antibodies (ABGA). One patient had motor tics and unusual motor stereotypies, 2 had multiple motor and vocal tics, and the remaining patient had motor tics only. Concomitant psychiatric disturbance was noted in 3 cases. In 2 cases, there was a close temporal relationship between upper respiratory tract infection and the subsequent onset of tics. Imaging was possible in three cases and was normal in two but revealed a lesion involving the right caudate and lentiform nuclei in the other. We suggest that there might be a causal relationship between ABGA and the clinical syndrome in these cases and that ABGA should be considered as a possible etiology for adult-onset tics.
Editeur
Wiley
Identifiant
PMID : 15390017 ISSN : 0885-3185
Source
Movement disorders A. 2004, vol. 19, n° 10, pp. 1190-1196 [7 pages] [bibl. : 33 ref.]
Langue
Anglais
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