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Stres oksydacyjny i rola witaminy E oraz selenu w zapobieganiu zatrzymania łoźyska u krÓw
Oxidative stress: the protective role of Vitamin E and selenium in retained placenta
The periparturient and early lactation periods are critical for the health of dairy cows. Udder edema, retained placenta, and suboptimal reproduction all reduce profits for dairy farmers. Reactive oxygen metabolites generated both during normal and xenobiotic stimulated metabolism can enter into reactions which, if uncontrolled, may impair health of dairy cows either directly or indirectly. Direct effects include peroxidative changes in membranes and other cellular components, including steroidogenic enzymes. Vitamin E plays a key protective role by quenching reactive oxygen metabolites and breaking peroxidative chains. The possible relationship between dietary antioxidants, oxidative status and placental retention in periparturient dairy cows has been presented. Inadequate dietary antioxidants, oxidative stress, production of lipid peroxides may increase the Incidence of retained fetal membranes. Prepartum supplementation with Vitamin E (1000 I.U./ day during the last 6 weeks of gestation) reduces incidence of placental retention by about 30%. Combined injection of Vitamin E and selenium is more effective in reducing this incidence. However, if the selenium content in feed is less than 0.12 ppm, the Vitamin E supplementation for cows may not be effective. Since Vitamin E contents in hay and silage decreases progressively with storage, a higher incidence of retained placenta in the spring, prior to the growing season, was noticed. Since the prevention and chain breaking antio
Polish Society of Veterinary Sciences
ISSN : 0025-8628
Medycyna Weterynaryjna A. 2003, vol. 59, n° 5, pp. 382-385 [4 pages]
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