Détail de la notice
Titre du Document
Health hazards due to the inhalation of amorphous silica
Auteur(s)
MERGET R. ; BAUER T. ; KÜPPER H. U. ; ...
Résumé
Occupational exposure to crystalline silica dust is associated with an increased risk for pulmonary diseases such as silicosis, tuberculosis, chronic bronchitis, chronic obstructive pulmonary disease (COPD) and lung cancer. This review summarizes the current knowledge about the health effects of amorphous (synonym: non-crystalline) forms of silica. The major problem in the assessment of health effects of amorphous silica is contamination with crystalline silica. This applies particularly to well documented pneumoconiosis among diatomaceous earth workers. Intentionally manufactured synthetic amorphous silicas are without contamination of crystalline silica. These may be classified as (1) wet process silica, (2) pyrogenic (thermal or fumed) silica, and (3) chemically or physically modified silica. According to the different physico-chemical properties, the major classes of synthetic amorphous silica are used in a variety of products, e.g. as fillers in the rubber industry, tyre compounds, free-flow and anti-caking agents in powder materials and liquid carriers, particularly in the manufacture of animal feed and agrochemicals, additives of toothpaste, paints, silicon rubber, insulation material, liquid systems in coatings, adhesives, printing inks, plastisol car undercoatings, and cosmetics. Animal inhalation studies with intentionally manufactured synthetic amorphous silica showed at least partially reversible inflammation, granuloma formation and emphysema, but no progressive
Editeur
Gordon and Breach
Identifiant
ISSN : 1061-0251
Source
Occupational hygiene (Print) A. 2001, vol. 5, n° 3, pp. 231-251 [bibl. : 60 ref.]
Langue
Anglais
Pour les membres de la communauté du CNRS, ce document est autorisé à la reproduction à titre gratuit.
Pour les membres des communautés hors CNRS, la reproduction de ce document à titre onéreux sera fournie sous réserve d’autorisation du Centre Français d’exploitation du droit de Copie.

Pour bénéficier de nos services (strictement destinés aux membres de la communauté CNRS (Centre National de la Recherche Scientifique), de l'ESR français (Enseignement Supérieur et Recherche), et du secteur public français & étranger) :